7DCF: Crystal structure of EHMT2 SET domain in complex with compound 10

PDB ID: 7DCFDownload
MMDB ID: 198645
PDB Deposition Date: 2020/10/26
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7DCF: dimeric; determined by author and by software (PISA)
Molecular Components in 7DCF
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase Ehmt2
(Gene symbol: EHMT2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
8
ZINC IONZINC ION
2
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
2
5'-methoxy-6'-(1-methyl-2,3,4,7-tetrahydroazepin-5-yl)spiro[cyclobutane-1,3'-indole]-2'-amine5'-methoxy-6'-(1-methyl-2,3,4,7-tetrahydroazepin-5-yl)spiro[cyclobutane-1,3'-indole]-2'-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303