7D93: Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ and anthroylouabain (P2(1)2(1)2(1) symmetry)

PDB ID: 7D93Download
MMDB ID: 198040
PDB Deposition Date: 2020/10/12
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.65  Å
Source Organism:
Similar Structures:
Biological Unit for 7D93: trimeric; determined by author and by software (PISA)
Molecular Components in 7D93
Label Count Molecule
Proteins (3 molecules)
1
Sodium/potassium-transporting Atpase Subunit Alpha-1
(Gene symbol: ATP1A1)
Molecule annotation
1
Sodium/potassium-transporting Atpase Subunit Beta-1
(Gene symbol: ATP1B1)
Molecule annotation
1
Fxyd Domain-containing Ion Transport Regulator
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
SODIUM IONSODIUM ION
4
3
CHOLESTEROLCHOLESTEROL
5
8
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
6
1
[(2~{R},3~{R},4~{R},5~{S},6~{S})-2-[[(1~{R},3~{S},5~{S},8~{R},9~{S},10~{R},11~{R},13~{R},14~{S},17~{R})-10-(hydroxymethyl)-13-methyl-1,5,11,14-tetrakis(oxidanyl)-17-(5-oxidanylidene-2~{H}-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl]oxy]-6-methyl-3,5-bis(oxidanyl)oxan-4-yl] anthracene-9-carboxylate[(2~{R},3~{R},4~{R},5~{S},6~{S})-2-[[(1~{R},3~{S},5~{S},8~{R},9~{S},10~{R},11~{R},13~{R},14~{S},17~{R})-10-(hydroxymethyl)-13-methyl-1,5,11,14-tetrakis(oxidanyl)-17-(5-oxidanylidene-2~{H}-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl]oxy]-6-methyl-3,5-bis(oxidanyl)oxan-4-yl] anthracene-9-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303