7D7M: Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein

PDB ID: 7D7MDownload
MMDB ID: 194807
PDB Deposition Date: 2020/10/5
Updated in MMDB: 2020/12
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Lama glama▼
Similar Structures:
Biological Unit for 7D7M: pentameric; determined by author
Molecular Components in 7D7M
Label Count Molecule
Proteins (5 molecules)
1
Prostaglandin E2 Receptor EP4 Subtype,prostaglandin E2 Receptor EP4 Subtype
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short,guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short,guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Nanobody Nb35
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303