7D76: Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex

PDB ID: 7D76Download
MMDB ID: 198289
PDB Deposition Date: 2020/10/3
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 7D76: tetrameric; determined by author
Molecular Components in 7D76
Label Count Molecule
Proteins (4 molecules)
1
Guanine Nucleotide-binding Protein G(o) Subunit Alpha
(Gene symbol: GNAO1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Adhesion G Protein-coupled Receptor G3; Gpr97
(Gene symbol: ADGRG3)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
PALMITIC ACIDPALMITIC ACID
2
1
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
3
1
(8~{S},9~{R},10~{S},11~{S},13~{S},14~{S},16~{S},17~{R})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one(8~{S},9~{R},10~{S},11~{S},13~{S},14~{S},16~{S},17~{R})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
4
2
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303