7D4P: Structure of human TRPC5 in complex with clemizole

PDB ID: 7D4PDownload
MMDB ID: 200411
PDB Deposition Date: 2020/9/24
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7D4P: tetrameric; determined by author
Molecular Components in 7D4P
Label Count Molecule
Proteins (4 molecules)
4
Short Transient Receptor Potential Channel 5
(Gene symbol: TRPC5)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
4
1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole
2
4
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
3
4
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
4
4
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
5
4
ZINC IONZINC ION
6
4
CALCIUM IONCALCIUM ION
7
4
(2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate(2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303