7D42: Structural basis of tropifexor as a potent and selective agonist for farnesoid X receptor

PDB ID: 7D42Download
MMDB ID: 195993
PDB Deposition Date: 2020/9/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.697  Å
Source Organism:
Similar Structures:
Biological Unit for 7D42: dimeric; determined by author and by software (PISA)
Molecular Components in 7D42
Label Count Molecule
Proteins (2 molecules)
1
Bile Acid Receptor
(Gene symbol: NR1H4)
Molecule annotation
1
Peptide From Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
TropifexorTropifexor
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303