7D3F: Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state

PDB ID: 7D3FDownload
MMDB ID: 196244
PDB Deposition Date: 2020/9/19
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7D3F: tetrameric; determined by author
Molecular Components in 7D3F
Label Count Molecule
Proteins (4 molecules)
2
Dual Oxidase 1
(Gene symbol: DUOX1)
Molecule annotation
2
Isoform 2 of Dual Oxidase Maturation Factor 1
(Gene symbol: DUOXA1)
Molecule annotation
Chemicals and Non-standard biopolymers (46 molecules)
1
14
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
14
alpha-D-mannopyranosealpha-D-mannopyranose
4
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
5
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
6
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
7
4
CALCIUM IONCALCIUM ION
8
4
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303