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Biotechnology Information

7CX2: Cryo-EM structure of the PGE2-bound EP2-Gs complex

PDB ID:

MMDB ID:

201622

PDB Deposition Date:

2020/9/1

Updated in MMDB:

2021/05

Experimental Method:

electron microscopy

Resolution:

2.8 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	N
Homo sapiens	R, A, B, G

Similar Structures:

Biological Unit for 7CX2: pentameric; determined by author

Molecular Components in 7CX2
Label	Count	Molecule
Proteins (5 molecules)
R	1	Prostaglandin E2 Receptor EP2 Subtype
A	1	Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
B	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
G	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
N	1	Nanobody-35
Chemical and Non-standard biopolymers (1 molecule)
1	1	(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid

* Click molecule labels to explore molecular sequence information.

Citing MMDB