7CWA: Crystal structure of PDE8A catalytic domain in complex with clofarabine

PDB ID: 7CWADownload
MMDB ID: 206072
PDB Deposition Date: 2020/8/27
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7CWA: monomeric; determined by author and by software (PISA)
Molecular Components in 7CWA
Label Count Molecule
Protein (1 molecule)
1
High Affinity Camp-specific and Ibmx-insensitive 3',5'-cyclic Phosphodiesterase 8A
(Gene symbol: PDE8A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303