7CL0: Crystal structure of human SIRT6

PDB ID: 7CL0Download
MMDB ID: 199115
PDB Deposition Date: 2020/7/20
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.53  Å
Source Organism:
Similar Structures:
Biological Unit for 7CL0: dimeric; determined by author
Molecular Components in 7CL0
Label Count Molecule
Proteins (2 molecules)
1
Nad-dependent Protein Deacetylase Sirtuin-6
(Gene symbol: SIRT6)
Molecule annotation
1
Thr-ala-arg-lys-ser-thr-gly
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
1
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
2
1
ZINC IONZINC ION
3
8
SULFATE IONSULFATE ION
4
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
tetradecanethialtetradecanethial
6
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303