7CKO: Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate 7ACC2 in the inward-open conformation

PDB ID: 7CKODownload
MMDB ID: 196843
PDB Deposition Date: 2020/7/18
Updated in MMDB: 2024/04
Experimental Method:
electron microscopy
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 7CKO: dimeric; determined by author
Molecular Components in 7CKO
Label Count Molecule
Proteins (2 molecules)
1
Monocarboxylate Transporter 1
(Gene symbol: SLC16A1)
Molecule annotation
1
Basigin
(Gene symbol: BSG)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
7-[methyl-(phenylmethyl)amino]-2-oxidanylidene-chromene-3-carboxylic acid7-[methyl-(phenylmethyl)amino]-2-oxidanylidene-chromene-3-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303