7CBJ: Crystal structure of PDE4D catalytic domain in complex with compound 36

PDB ID: 7CBJDownload
MMDB ID: 203154
PDB Deposition Date: 2020/6/12
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7CBJ: dimeric; determined by author
Molecular Components in 7CBJ
Label Count Molecule
Proteins (2 molecules)
2
Camp-specific 3',5'-cyclic Phosphodiesterase 4D
(Gene symbol: PDE4D)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
2
ZINC IONZINC ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
(1S)-1-[(7-chloranyl-1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbaldehyde(1S)-1-[(7-chloranyl-1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbaldehyde
4
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303