7C44: Crystal structure of the p53-binding domain of human MdmX protein in complex with Nutlin3a

PDB ID: 7C44Download
MMDB ID: 189139
PDB Deposition Date: 2020/5/15
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 7C44: monomeric; determined by author
Molecular Components in 7C44
Label Count Molecule
Protein (1 molecule)
1
Protein Mdm4
(Gene symbol: MDM4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one
2
1
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303