National Center for
Biotechnology Information

7C0M: Human cGAS-nucleosome complex

PDB ID:

MMDB ID:

192482

PDB Deposition Date:

2020/5/1

Updated in MMDB:

2022/11

Experimental Method:

electron microscopy

Resolution:

3.9 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	I, J, i, j
Homo sapiens	A, B, C, D, E, F, G, H, K, a, b, c, d, e, f, g, h, k

Similar Structures:

Biological Unit for 7C0M: 22-meric; determined by author

Molecular Components in 7C0M
Label	Count	Molecule
Proteins (18 molecules)
A E a e	4	Histone H3.1
B F b f	4	Histone H4
C G c g	4	Histone H2A Type 1-b/e
D H d h	4	Histone H2B Type 1-J
K k	2	Cyclic Gmp-amp Synthase
Nucleotides(4 molecules)
I i	2	DNA (145-mer)
J j	2	DNA (145-mer)
Chemicals and Non-standard biopolymers (2 molecules)
1	2	ZINC ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB