7BV2: The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP)

PDB ID: 7BV2Download
MMDB ID: 188121
PDB Deposition Date: 2020/4/9
Updated in MMDB: 2020/10
Experimental Method:
electron microscopy
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7BV2: pentameric; determined by author
Molecular Components in 7BV2
Label Count Molecule
Proteins (3 molecules)
1
RNA-directed RNA Polymerase
Molecule annotation
1
Non-structural Protein 8
Molecule annotation
1
Non-structural Protein 7
Molecule annotation
Nucleotides(2 molecules)
1
Primer
Molecule annotation
1
Templete
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
1
PYROPHOSPHATE 2-PYROPHOSPHATE 2-
3
2
MAGNESIUM IONMAGNESIUM ION
4
1
[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303