7BUC: Crystal structure of EHMT2 SET domain in complex with compound 13

PDB ID: 7BUCDownload
MMDB ID: 195149
PDB Deposition Date: 2020/4/6
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7BUC: dimeric; determined by author and by software (PISA)
Molecular Components in 7BUC
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase Ehmt2
(Gene symbol: EHMT2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
8
ZINC IONZINC ION
2
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
2
N2-[4-methoxy-3-(2,3,4,7-tetrahydro-1H-azepin-5-yl)phenyl]-N4,6-dimethyl-pyrimidine-2,4-diamineN2-[4-methoxy-3-(2,3,4,7-tetrahydro-1H-azepin-5-yl)phenyl]-N4,6-dimethyl-pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303