7BLE: Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with the tricyclic inhibitor (3)

PDB ID: 7BLEDownload
MMDB ID: 199889
PDB Deposition Date: 2021/1/18
Updated in MMDB: 2021/03
Experimental Method:
x-ray diffraction
Resolution: 2.809  Å
Source Organism:
Similar Structures:
Biological Unit for 7BLE: monomeric; determined by author
Molecular Components in 7BLE
Label Count Molecule
Protein (1 molecule)
1
Nicotinamide N-methyltransferase
(Gene symbol: NNMT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
1
3-ethyl-1,3-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-2-imine3-ethyl-1,3-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-2-imine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303