7BHX: Crystal structure of MAT2a bound to allosteric inhibitor (compound 31)

PDB ID: 7BHXDownload
MMDB ID: 201173
PDB Deposition Date: 2021/1/11
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.08  Å
Source Organism:
Similar Structures:
Biological Unit for 7BHX: dimeric; determined by author and by software (PISA)
Molecular Components in 7BHX
Label Count Molecule
Proteins (2 molecules)
2
S-adenosylmethionine Synthase Isoform Type-2
(Gene symbol: MAT2A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
2
7-chloranyl-4-(dimethylamino)-1-pyridin-3-yl-quinazolin-2-one7-chloranyl-4-(dimethylamino)-1-pyridin-3-yl-quinazolin-2-one
3
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
4
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303