7BFZ: X-ray structure of human prostate-specific membrane antigen(PSMA) in complex with a inhibitor Glu-490

PDB ID: 7BFZDownload
MMDB ID: 205651
PDB Deposition Date: 2021/1/5
Updated in MMDB: 2022/08
Experimental Method:
x-ray diffraction
Resolution: 1.73  Å
Source Organism:
Similar Structures:
Biological Unit for 7BFZ: dimeric; determined by author and by software (PISA)
Molecular Components in 7BFZ
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Carboxypeptidase 2
(Gene symbol: FOLH1)
Molecule annotation
Chemicals and Non-standard biopolymers (44 molecules)
1
18
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
alpha-L-fucopyranosealpha-L-fucopyranose
3
2
beta-D-mannopyranosebeta-D-mannopyranose
4
4
ZINC IONZINC ION
5
2
CALCIUM IONCALCIUM ION
6
2
CHLORIDE IONCHLORIDE ION
7
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
8
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
9
4
SODIUM IONSODIUM ION
10
2
(((S)-1-carboxy-5-((E)-2-cyano-3-(5-(1-(3-methoxy-3-oxopropyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophen-2-yl)acrylamido)pentyl)carbamoyl)-L-glutamic acid(((S)-1-carboxy-5-((E)-2-cyano-3-(5-(1-(3-methoxy-3-oxopropyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophen-2-yl)acrylamido)pentyl)carbamoyl)-L-glutamic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303