7BE6: Structure of DDR1 receptor tyrosine kinase in complex with inhibitor SR159

PDB ID: 7BE6Download
MMDB ID: 199350
PDB Deposition Date: 2020/12/22
Updated in MMDB: 2022/09
Experimental Method:
x-ray diffraction
Resolution: 1.87082  Å
Source Organism:
Similar Structures:
Biological Unit for 7BE6: monomeric; determined by author and by software (PISA)
Molecular Components in 7BE6
Label Count Molecule
Protein (1 molecule)
1
Epithelial Discoidin Domain-containing Receptor 1
(Gene symbol: DDR1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
PHOSPHATE IONPHOSPHATE ION
3
1
SULFATE IONSULFATE ION
4
1
5-amino-N-(4-(((2S)-4-cyclohexyl-1-((1-(methylsulfonyl)piperidin-3-yl)amino)-1-oxobutan-2-yl)carbamoyl)benzyl)-1-phenyl-1H-pyrazole-4-carboxamide5-amino-N-(4-(((2S)-4-cyclohexyl-1-((1-(methylsulfonyl)piperidin-3-yl)amino)-1-oxobutan-2-yl)carbamoyl)benzyl)-1-phenyl-1H-pyrazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303