National Center for
Biotechnology Information

7B7U: Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2

PDB ID:

MMDB ID:

202075

PDB Deposition Date:

2020/12/11

Updated in MMDB:

2025/12

Experimental Method:

electron microscopy

Resolution:

2.8 Å

Source Organism:

Sus scrofa domesticus▼

Taxonomy	Molecule
Sus scrofa domesticus	A, B, C, E, F, H, I, J, K, L
Homo sapiens	M, N

Similar Structures:

Biological Unit for 7B7U: dodecameric; determined by author and by software (PISA)

Molecular Components in 7B7U
Label	Count	Molecule
Proteins (12 molecules)
A	1	DNA-directed RNA Polymerase Subunit
B	1	DNA-directed RNA Polymerase Subunit Beta
C	1	DNA-directed RNA Polymerase II Subunit Rpb3
E	1	DNA-directed RNA Polymerase II Subunit E
F	1	DNA-directed RNA Polymerase II Subunit F
H	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc3
I	1	DNA-directed RNA Polymerase II Subunit Rpb9
J	1	Uncharacterized Protein
K	1	RNA_pol_l_2 Domain-containing Protein
L	1	RNA Polymerase II Subunit K
M	1	Putative RNA Polymerase II Subunit B1 CTD Phosphatase Rpap2
N	1	Unknown
Chemicals and Non-standard biopolymers (6 molecules)
1	6	ZINC ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB