7B5O: Cryo-EM structure of the human CAK bound to ICEC0942 at 2.5 Angstroms resolution

PDB ID: 7B5ODownload
MMDB ID: 198598
PDB Deposition Date: 2020/12/5
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7B5O: trimeric; determined by author and by software (PISA)
Molecular Components in 7B5O
Label Count Molecule
Proteins (3 molecules)
1
Cdk-activating Kinase Assembly Factor Mat1
(Gene symbol: MNAT1)
Molecule annotation
1
Cyclin-h
(Gene symbol: CCNH)
Molecule annotation
1
Cyclin-dependent Kinase 7
(Gene symbol: CDK7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol(3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303