7B16: TRPC4 in complex with inhibitor GFB-9289

PDB ID: 7B16Download
MMDB ID: 196221
PDB Deposition Date: 2020/11/23
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 3.15  Å
Source Organism:
Similar Structures:
Biological Unit for 7B16: tetrameric; determined by author
Molecular Components in 7B16
Label Count Molecule
Proteins (4 molecules)
4
Transient Receptor Potential Cation Channel Subfamily C Member 4A
(Gene symbol: trpc4b)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one
2
4
CALCIUM IONCALCIUM ION
3
4
2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303