7AY6: Crystal structure of the PDE4D catalytic domain in complex with GEBR-41b

PDB ID: 7AY6Download
MMDB ID: 203704
PDB Deposition Date: 2020/11/11
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.66  Å
Source Organism:
Similar Structures:
Biological Unit for 7AY6: dimeric; determined by author and by software (PISA)
Molecular Components in 7AY6
Label Count Molecule
Proteins (2 molecules)
2
Camp-specific 3',5'-cyclic Phosphodiesterase 4D
(Gene symbol: PDE4D)
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
2
2-[(~{Z})-1-(3-cyclopentyloxy-4-methoxy-phenyl)ethylideneamino]oxy-1-[(2~{S},6~{S})-2,6-dimethylmorpholin-4-yl]ethanone2-[(~{Z})-1-(3-cyclopentyloxy-4-methoxy-phenyl)ethylideneamino]oxy-1-[(2~{S},6~{S})-2,6-dimethylmorpholin-4-yl]ethanone
2
2
ZINC IONZINC ION
3
8
MAGNESIUM IONMAGNESIUM ION
4
14
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303