7AW3: MerTK kinase domain with type 1 inhibitor from a DNA-encoded library

PDB ID: 7AW3Download
MMDB ID: 199327
PDB Deposition Date: 2020/11/6
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.99  Å
Source Organism:
Similar Structures:
Biological Unit for 7AW3: monomeric; determined by author
Molecular Components in 7AW3
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase MER
(Gene symbol: MERTK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-(1-((5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxamido)methyl)-2-azabicyclo[2.1.1]hexan-2-yl)-N-methyl-4-(trifluoromethyl)thiazole-5-carboxamide2-(1-((5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxamido)methyl)-2-azabicyclo[2.1.1]hexan-2-yl)-N-methyl-4-(trifluoromethyl)thiazole-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303