7AT8: Histone H3 recognition by nucleosome-bound PRC2 subunit EZH2

PDB ID: 7AT8Download
MMDB ID: 196216
PDB Deposition Date: 2020/10/29
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 4.4  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7AT8: dodecameric; determined by author and by software (PISA)
Molecular Components in 7AT8
Label Count Molecule
Proteins (10 molecules)
1
Isoform 2 of Histone-lysine N-methyltransferase Ezh2,isoform 2 of Histone-lysine N-methyltransferase Ezh2,histone-lysine N-methyltransferase Ezh2,isoform 2 of Histone-lysine N-methyltransferase Ezh2,isoform 2 of Histone-lysine N-methyltransferase Ezh2
Molecule annotation
1
Polycomb Protein Suz12
Molecule annotation
2
Histone H3.2
Molecule annotation
2
Histone H4
Molecule annotation
2
Histone H2A
Molecule annotation
2
Histone H2B 1.1
Molecule annotation
Nucleotides(2 molecules)
1
Widom601 DNA Plus Linker
Molecule annotation
1
Widom601 DNA Plus Linker
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
7
ZINC IONZINC ION
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303