7AS2: Influenza A PB2 (M431 mutation) in complex with VX-787

PDB ID: 7AS2Download
MMDB ID: 199098
PDB Deposition Date: 2020/10/26
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 7AS2: monomeric; determined by author and by software (PISA)
Molecular Components in 7AS2
Label Count Molecule
Protein (1 molecule)
1
Polymerase Basic Protein 2
(Gene symbol: PB2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid(2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303