7ARO: Crystal structure of the non-ribose partial agonist LUF5833 bound to the adenosine A2A receptor

PDB ID: 7ARODownload
MMDB ID: 200625
PDB Deposition Date: 2020/10/25
Updated in MMDB: 2021/04
Experimental Method:
x-ray diffraction
Resolution: 3.119  Å
Source Organism:
Similar Structures:
Biological Unit for 7ARO: dimeric; determined by author and by software (PISA)
Molecular Components in 7ARO
Label Count Molecule
Proteins (2 molecules)
2
Adenosine Receptor A2a,soluble Cytochrome B562,adenosine Receptor A2A
(Gene symbol: ADORA2A)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
2-azanyl-6-(1~{H}-imidazol-2-ylmethylsulfanyl)-4-phenyl-pyridine-3,5-dicarbonitrile2-azanyl-6-(1~{H}-imidazol-2-ylmethylsulfanyl)-4-phenyl-pyridine-3,5-dicarbonitrile
2
8
OLEIC ACIDOLEIC ACID
3
2
CHOLESTEROLCHOLESTEROL
4
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303