7AQG: Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F)

PDB ID: 7AQGDownload
MMDB ID: 199095
PDB Deposition Date: 2020/10/21
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.27  Å
Source Organism:
Vicugna pacos▼
Similar Structures:
Biological Unit for 7AQG: trimeric; determined by author and by software (PISA)
Molecular Components in 7AQG
Label Count Molecule
Proteins (3 molecules)
1
Plasminogen Activator Inhibitor 1
Molecule annotation
1
Vhh-2g-42 (Nb42)
Molecule annotation
1
Vhh-2w-64 (Nb64)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303