7AQ1: Crystal structure of human mature meprin beta in complex with the specific inhibitor MWT-S-270

PDB ID: 7AQ1Download
MMDB ID: 199310
PDB Deposition Date: 2020/10/20
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 2.413  Å
Source Organism:
Similar Structures:
Biological Unit for 7AQ1: dimeric; determined by author and by software (PISA)
Molecular Components in 7AQ1
Label Count Molecule
Proteins (2 molecules)
2
Meprin B Subunit Beta
(Gene symbol: MEP1B)
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
13
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
11
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
ZINC IONZINC ION
5
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
2
3-[[(3-Carboxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acid3-[[(3-Carboxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acid
7
4
CALCIUM IONCALCIUM ION
8
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303