7AOS: crystal structure of the RARalpha/RXRalpha ligand binding domain heterodimer in complex with a fragment of SRC1 coactivator

PDB ID: 7AOSDownload
MMDB ID: 205148
PDB Deposition Date: 2020/10/15
Updated in MMDB: 2021/08
Experimental Method:
x-ray diffraction
Resolution: 2.55  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 7AOS: tetrameric; determined by author and by software (PISA)
Molecular Components in 7AOS
Label Count Molecule
Proteins (4 molecules)
1
Retinoic Acid Receptor Rxr-alpha
Molecule annotation
1
Retinoic Acid Receptor Alpha
Molecule annotation
2
Nuclear Receptor Coactivator 1
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID
2
1
GLYCEROLGLYCEROL
3
1
4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303