7AOP: Structure of NUDT15 in complex with inhibitor TH8321

PDB ID: 7AOPDownload
MMDB ID: 202627
PDB Deposition Date: 2020/10/14
Updated in MMDB: 2022/12
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 7AOP: dimeric; determined by author and by software (PISA)
Molecular Components in 7AOP
Label Count Molecule
Proteins (2 molecules)
2
Nucleotide Triphosphate Diphosphatase Nudt15
(Gene symbol: NUDT15)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2-azanyl-9-cyclohexyl-8-(2-methoxyphenyl)-3~{H}-purine-6-thione2-azanyl-9-cyclohexyl-8-(2-methoxyphenyl)-3~{H}-purine-6-thione
2
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303