7AML: RET/GDNF/GFRa1 extracellular complex Cryo-EM structure

PDB ID: 7AMLDownload
MMDB ID: 197497
PDB Deposition Date: 2020/10/9
Updated in MMDB: 2021/07
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7AML: hexameric; determined by author
Molecular Components in 7AML
Label Count Molecule
Proteins (6 molecules)
2
Proto-oncogene Tyrosine-protein Kinase Receptor RET
(Gene symbol: ret)
Molecule annotation
2
Gdnf Family Receptor Alpha
(Gene symbol: gfra1a)
Molecule annotation
2
Glial Cell Line-derived Neurotrophic Factor
(Gene symbol: gdnfa)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
8
CALCIUM IONCALCIUM ION
2
16
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303