7AK2: Structure of DYRK1A in complex with compound 53

PDB ID: 7AK2Download
MMDB ID: 202381
PDB Deposition Date: 2020/9/29
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 7AK2: monomeric; determined by author
Molecular Components in 7AK2
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-[2-methyl-3-(2-pyridin-2-yloxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine4-[2-methyl-3-(2-pyridin-2-yloxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
2
1
PHOSPHATE IONPHOSPHATE ION
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303