7AK0: Human MALT1(329-729) in complex with a chromane urea containing inhibitor

PDB ID: 7AK0Download
MMDB ID: 196207
PDB Deposition Date: 2020/9/29
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.316  Å
Source Organism:
Similar Structures:
Biological Unit for 7AK0: dimeric; determined by author and by software (PISA)
Molecular Components in 7AK0
Label Count Molecule
Proteins (2 molecules)
2
Mucosa-associated Lymphoid Tissue Lymphoma Translocation Protein 1
(Gene symbol: MALT1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-[4-[4-(aminomethyl)pyrazol-1-yl]-3-chloranyl-phenyl]-3-[(3~{R})-6-bromanyl-3,4-dihydro-2~{H}-chromen-3-yl]urea1-[4-[4-(aminomethyl)pyrazol-1-yl]-3-chloranyl-phenyl]-3-[(3~{R})-6-bromanyl-3,4-dihydro-2~{H}-chromen-3-yl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303