7ADV: Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ447 (compound 6v)

PDB ID: 7ADVDownload
MMDB ID: 200086
PDB Deposition Date: 2020/9/16
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7ADV: octameric; determined by author
Molecular Components in 7ADV
Label Count Molecule
Proteins (4 molecules)
4
Integrase
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*cp*gp*cp*a)-3')
Molecule annotation
2
DNA (5'-d(*tp*gp*cp*gp*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (61 molecules)
1
6
MAGNESIUM IONMAGNESIUM ION
2
2
ZINC IONZINC ION
3
2
4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[2-(2-morpholin-4-ylethylsulfonyl)ethyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[2-(2-morpholin-4-ylethylsulfonyl)ethyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide
4
36
SULFATE IONSULFATE ION
5
15
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303