7ADU: Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ440 (compound 5j)

PDB ID: 7ADUDownload
MMDB ID: 200085
PDB Deposition Date: 2020/9/16
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.62  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7ADU: octameric; determined by author and by software (PISA)
Molecular Components in 7ADU
Label Count Molecule
Proteins (4 molecules)
4
Integrase
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*cp*gp*cp*a)-3')
Molecule annotation
2
DNA (5'-d(*tp*gp*cp*gp*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (44 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-5-(hydroxymethyl)-1,4-bis(oxidanyl)-2-oxidanylidene-1,8-naphthyridine-3-carboxamide~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-5-(hydroxymethyl)-1,4-bis(oxidanyl)-2-oxidanylidene-1,8-naphthyridine-3-carboxamide
3
2
ZINC IONZINC ION
4
22
SULFATE IONSULFATE ION
5
12
GLYCEROLGLYCEROL
6
2
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303