7ACK: CDK2/cyclin A2 in complex with an imidazo[1,2-c]pyrimidin-5-one inhibitor

PDB ID: 7ACKDownload
MMDB ID: 200084
PDB Deposition Date: 2020/9/11
Updated in MMDB: 2021/03
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7ACK: dimeric; determined by author
Molecular Components in 7ACK
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
8-cyclohexyl-6~{H}-imidazo[1,2-c]pyrimidin-5-one8-cyclohexyl-6~{H}-imidazo[1,2-c]pyrimidin-5-one
2
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303