7AC8: Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex

PDB ID: 7AC8Download
MMDB ID: 202055
PDB Deposition Date: 2020/9/10
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 2.06  Å
Source Organism:
Thermotoga maritima MSB8▼
Similar Structures:
Biological Unit for 7AC8: dimeric; determined by author
Molecular Components in 7AC8
Label Count Molecule
Proteins (2 molecules)
1
Imidazole Glycerol Phosphate Synthase Subunit Hisf
Molecule annotation
1
Imidazole Glycerol Phosphate Synthase Subunit Hish
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
[(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate[(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
2
1
GLUTAMINEGLUTAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303