7AB2: Crystal structure of MerTK kinase domain in complex with UNC2025

PDB ID: 7AB2Download
MMDB ID: 194463
PDB Deposition Date: 2020/9/5
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 7AB2: monomeric; determined by author
Molecular Components in 7AB2
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase MER
(Gene symbol: MERTK)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
4-[2-(butylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol4-[2-(butylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol
2
4
CHLORIDE IONCHLORIDE ION
3
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303