7AAZ: Crystal structure of MerTK in complex with a type 1.5 aminopyridine inhibitor

PDB ID: 7AAZDownload
MMDB ID: 195341
PDB Deposition Date: 2020/9/5
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.855  Å
Source Organism:
Similar Structures:
Biological Unit for 7AAZ: monomeric; determined by author
Molecular Components in 7AAZ
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase MER
(Gene symbol: MERTK)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
2-azanyl-~{N}-[(1~{S},2~{S})-2-[[4-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]methoxy]cyclopentyl]-5-(1-methylpyrazol-4-yl)pyridine-3-carboxamide2-azanyl-~{N}-[(1~{S},2~{S})-2-[[4-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]methoxy]cyclopentyl]-5-(1-methylpyrazol-4-yl)pyridine-3-carboxamide
2
6
CHLORIDE IONCHLORIDE ION
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303