7AAX: Crystal structure of MerTK kinase domain in complex with LDC1267

PDB ID: 7AAXDownload
MMDB ID: 194459
PDB Deposition Date: 2020/9/5
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.762  Å
Source Organism:
Similar Structures:
Biological Unit for 7AAX: monomeric; determined by author
Molecular Components in 7AAX
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase MER
(Gene symbol: MERTK)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
~{N}-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluoranyl-phenyl]-4-ethoxy-1-(4-fluoranyl-2-methyl-phenyl)pyrazole-3-carboxamide~{N}-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluoranyl-phenyl]-4-ethoxy-1-(4-fluoranyl-2-methyl-phenyl)pyrazole-3-carboxamide
2
3
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303