7AAP: Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP

PDB ID: 7AAPDownload
MMDB ID: 199190
PDB Deposition Date: 2020/9/4
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7AAP: hexameric; determined by author and by software (PISA)
Molecular Components in 7AAP
Label Count Molecule
Proteins (4 molecules)
1
Non-structural Protein 12
Molecule annotation
2
Non-structural Protein 8
Molecule annotation
1
Non-structural Protein 7
Molecule annotation
Nucleotides(2 molecules)
1
RNA (5'-r(p*up*up*ap*ap*gp*up*up*ap*u)-3')
Molecule annotation
1
RNA (5'-r(p*up*up*cp*ap*up*ap*ap*cp*up*up*ap*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
ZINC IONZINC ION
2
3
MAGNESIUM IONMAGNESIUM ION
3
1
PYROPHOSPHATE 2-PYROPHOSPHATE 2-
4
1
[[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonyl-5-fluoranyl-2-oxidanylidene-pyrazin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate[[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonyl-5-fluoranyl-2-oxidanylidene-pyrazin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303