7A6Q: Crystal structure of human aldehyde dehydrogenase 1A3 in complex with selective NR6 inhibitor compound

PDB ID: 7A6QDownload
MMDB ID: 198873
PDB Deposition Date: 2020/8/26
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 7A6Q: dimeric; determined by author and by software (PISA)
Molecular Components in 7A6Q
Label Count Molecule
Proteins (2 molecules)
2
Aldehyde Dehydrogenase Family 1 Member A3
(Gene symbol: ALDH1A3)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
2
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
2
3-(2-phenylimidazo[1,2-a]pyridin-6-yl)benzenecarbonitrile3-(2-phenylimidazo[1,2-a]pyridin-6-yl)benzenecarbonitrile
3
4
SODIUM IONSODIUM ION
4
7
GLYCEROLGLYCEROL
5
1
(3-oxidanylidene-3-sodiooxy-propanoyl)oxysodium(3-oxidanylidene-3-sodiooxy-propanoyl)oxysodium
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303