7A5V: CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc

PDB ID: 7A5VDownload
MMDB ID: 194759
PDB Deposition Date: 2020/8/22
Updated in MMDB: 2020/12
Experimental Method:
electron microscopy
Resolution: 1.7  Å
Source Organism:
Lama glama▼
Similar Structures:
Biological Unit for 7A5V: dimeric; determined by author and by software (author_and_software_defined_assembly)
Molecular Components in 7A5V
Label Count Molecule
Proteins (2 molecules)
1
Gamma-aminobutyric Acid Receptor Subunit Beta-3,gamma-aminobutyric Acid Receptor Subunit Beta-3
Molecule annotation
1
Megabody Mb25
Molecule annotation
Chemicals and Non-standard biopolymers (70 molecules)
1
20
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
beta-D-mannopyranosebeta-D-mannopyranose
3
5
alpha-D-mannopyranosealpha-D-mannopyranose
4
5
HEXADECANEHEXADECANE
5
20
DECANEDECANE
6
5
N-OCTANEN-OCTANE
7
5
HISTAMINEHISTAMINE
8
5
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303