7A5D: Structure of DYRK1A in complex with compound 16

PDB ID: 7A5DDownload
MMDB ID: 203695
PDB Deposition Date: 2020/8/21
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7A5D: monomeric; determined by author and by software (PISA)
Molecular Components in 7A5D
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
1
4-azanyl-2-methyl-6-pyridin-3-yl-7~{H}-pyrrolo[2,3-d]pyrimidine-5-carbonitrile4-azanyl-2-methyl-6-pyridin-3-yl-7~{H}-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303