7A41: MALT1 in complex with a NVS-MALT1 chemical probe

PDB ID: 7A41Download
MMDB ID: 195910
PDB Deposition Date: 2020/8/19
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.13  Å
Source Organism:
Similar Structures:
Biological Unit for 7A41: dimeric; determined by author and by software (PISA)
Molecular Components in 7A41
Label Count Molecule
Proteins (2 molecules)
2
Mucosa-associated Lymphoid Tissue Lymphoma Translocation Protein 1
(Gene symbol: MALT1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
~{N}-[(1~{S})-1-[4-[[2-chloranyl-7-[(1~{S})-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]amino]phenyl]-2,2,2-tris(fluoranyl)ethyl]-~{N}-methyl-1,1-bis(oxidanylidene)thiane-4-carboxamide~{N}-[(1~{S})-1-[4-[[2-chloranyl-7-[(1~{S})-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]amino]phenyl]-2,2,2-tris(fluoranyl)ethyl]-~{N}-methyl-1,1-bis(oxidanylidene)thiane-4-carboxamide
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303