7A3K: Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1

PDB ID: 7A3KDownload
MMDB ID: 203974
PDB Deposition Date: 2020/8/18
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 7A3K: dimeric; determined by author and by software (PISA)
Molecular Components in 7A3K
Label Count Molecule
Proteins (2 molecules)
2
Dipeptidyl Peptidase 8
(Gene symbol: DPP8)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
trimethylamine oxidetrimethylamine oxide
2
5
CHLORIDE IONCHLORIDE ION
3
2
SODIUM IONSODIUM ION
4
2
1-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]azetidin-2-one1-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]azetidin-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303