6ZYM: Human C Complex Spliceosome - High-resolution CORE

PDB ID: 6ZYMDownload
MMDB ID: 194228
PDB Deposition Date: 2020/8/2
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZYM: 26-meric; determined by author
Molecular Components in 6ZYM
Label Count Molecule
Proteins (21 molecules)
1
Corepressor Interacting With Rbpj 1
(Gene symbol: CIR1)
Molecule annotation
1
Pre-mrna-processing-splicing Factor 8
(Gene symbol: PRPF8)
Molecule annotation
1
116 KDA U5 Small Nuclear Ribonucleoprotein Component
(Gene symbol: EFTUD2)
Molecule annotation
1
SNW Domain-containing Protein 1
(Gene symbol: SNW1)
Molecule annotation
1
Pleiotropic Regulator 1
(Gene symbol: PLRG1)
Molecule annotation
1
Pre-mrna-processing Factor 17
(Gene symbol: CDC40)
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 40 KDA Protein
(Gene symbol: SNRNP40)
Molecule annotation
1
Cell Division Cycle 5-like Protein
(Gene symbol: CDC5L)
Molecule annotation
1
Crooked Neck-like Protein 1
(Gene symbol: CRNKL1)
Molecule annotation
1
Pre-mrna-splicing Factor Rbm22
(Gene symbol: RBM22)
Molecule annotation
1
Protein Bud31 Homolog
(Gene symbol: BUD31)
Molecule annotation
1
Spliceosome-associated Protein Cwc15 Homolog
(Gene symbol: CWC15)
Molecule annotation
1
Serine/arginine Repetitive Matrix Protein 2
(Gene symbol: SRRM2)
Molecule annotation
1
Pre-mrna-splicing Factor Cwc22 Homolog
(Gene symbol: CWC22)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase-like 1
(Gene symbol: PPIL1)
Molecule annotation
1
WD Repeat-containing Protein 70
(Gene symbol: WDR70)
Molecule annotation
1
Pre-mrna-splicing Factor Atp-dependent RNA Helicase Prp16
(Gene symbol: DHX38)
Molecule annotation
1
Pre-mrna-splicing Factor Isy1 Homolog
(Gene symbol: ISY1)
Molecule annotation
1
Pre-mrna-splicing Factor Cwc25 Homolog
(Gene symbol: CWC25)
Molecule annotation
1
Splicing Factor Yju2
(Gene symbol: YJU2)
Molecule annotation
1
Protein Frg1
(Gene symbol: FRG1)
Molecule annotation
Nucleotides(5 molecules)
1
U2 Snrna
Molecule annotation
1
U5 Snrna
Molecule annotation
1
U6 Snrna
Molecule annotation
2
Pre-mrna
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
5
1
1
7
* Click molecule labels to explore molecular sequence information.

Citing MMDB