6ZQZ: [1,2,4]Triazolo[1,5-a]pyrimidine Phosphodiesterase 2 Inhibitors

PDB ID: 6ZQZDownload
MMDB ID: 195335
PDB Deposition Date: 2020/7/10
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.88  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZQZ: dimeric; determined by author and by software (PISA)
Molecular Components in 6ZQZ
Label Count Molecule
Proteins (2 molecules)
2
Cgmp-dependent 3',5'-cyclic Phosphodiesterase
(Gene symbol: PDE2A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
5-[bis(fluoranyl)methyl]-7-[(3~{S})-1-[(2-chloranyl-6-methyl-pyridin-4-yl)methyl]piperidin-3-yl]-[1,2,4]triazolo[1,5-a]pyrimidine5-[bis(fluoranyl)methyl]-7-[(3~{S})-1-[(2-chloranyl-6-methyl-pyridin-4-yl)methyl]piperidin-3-yl]-[1,2,4]triazolo[1,5-a]pyrimidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303